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Our Science

Our Approach

Our team deploys state-of-the-art drug discovery modalities to identify novel, first-in-class antivirals for the individual infections we study. These modalities include phenotypic screening in infected cultured cells, biochemical screening in vitro on virus-encoded enzymatic targets and structure-based drug design, as well as combinations of the above approaches. Where appropriate, we also target host factors essential for viral infection.

Via Nova_H3N2_influenza_virus_particles

The application of these approaches has generated specific antiviral programs targeting influenza, rhinovirus, BK virus, and adenovirus.

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